Low-Carb Deconstructed Pizza Casserole is a delicious comfort food dinner that the whole family is going to love. And this Keto pizza casserole is one of the most popular casserole recipes on my blog!

PIN the Keto Pizza Casserole to try it later!

Low-Carb Deconstructed Pizza Casserole shown in baking dish

Low-Carb Deconstructed Pizza Casserole has been a hit with so many of my readers that it’s one of the most popular low-carb pizza casseroles on the internet! And this recipe is also perfect if you want a Keto Pizza Casserole.

If you struggle with feeling deprived when you give up carbs, I promise that this pizza casserole without the crust is a low-carb and Keto comfort food recipe that’s going to feel like a treat. And when the weather starts to get colder in the fall, everyone needs comfort food so I’m reminding you about this recipe for today’s Friday Favorites pick.

When the idea for a casserole with pizza flavors popped into my mind, I couldn’t wait to make it. Then when the casserole was cooking I couldn’t wait to eat it, and when I tried it I couldn’t wait to share the recipe. This is a dinner I’ve made many times at my house. And I promise this deconstructed pizza will be a hit when you’re craving pizza but don’t want the carbs! I hope you enjoy trying it.

What ingredients do you need for this recipe?

(This is only a list of ingredients; please scroll down for complete printable recipe. Or if you use the JUMP TO RECIPE link at the top of the page, it will take you directly to the complete recipe with ingredient amounts.)

  • can of diced tomatoes
  • uncooked turkey or pork Italian sausage
  • Olive Oil (affiliate link)
  • Dried Oregano (affiliate link)
  • salt and fresh-ground pepper to taste
  • fresh mushrooms
  • grated Mozzarella cheese
  • slices of pepperoni

How low in carbs is this Keto Pizza Casserole recipe?

This amazing deconstructed pizza casserole has only 4 net carbs and 26 grams of protein per serving!

Can you use other toppings for this low-carb Pizza Casserole?

Sausage, pepperoni, and cheese are the pizza toppings I love most, so of course that’s what I used for this Keto pizza casserole recipe! But you can definitely replace the sausage with ground beef or use other toppings like ham, green bell pepper, olives, or even bacon if you want to switch it up. And if you look in the comments on the post you’ll notice that people make it with a variety of toppings.

Can you freeze the Deconstructed Pizza Casserole?

Like most casserole recipes, this pizza casserole will freeze well and can be reheated in the microwave or a hot oven. Unfortunately at my house it usually disappears before I can get any in the freezer!

recipe steps collage for Low-Carb Deconstructed Pizza Casserole

How to Make Low-Carb Deconstructed Pizza Casserole:

(This is only a summary of the steps for the recipe; please scroll down for complete printable recipe. Or if you use the JUMP TO RECIPE link at the top of the page, it will take you directly to the complete recipe.)

  1. Dump a can of diced tomatoes into a colander and rinse; then spread them out to dry on a paper towel.
  2. Squeeze turkey Italian sausage out of the casings and brown well, then put it into a small casserole dish.
  3. Put the drained tomatoes over the sausage and season.
  4. Wash the mushrooms, pat dry, and cut into thick slices.
  5. Saute mushrooms until they give up their liquid and are starting to brown.
  6. Then layer mushrooms over the sausage-tomato mixture.
  7. Cut pepperoni in half (I use kitchen shears. (affiliate link)
  8. Spread the grated mozzarella over the casserole and top with pepperoni.
  9. Bake about 25 minutes, or until the ingredients are heated through and the cheese is starting to brown. (I baked mine a bit too long, don’t get distracted!)
  10. Serve the low-carb and Keto pizza casserole hot and enjoy! And I promise this will hit the spot any time you’re really craving pizza.

Make it a Low-Carb Meal:

Pizza Casserole may be a good low-carb or Keto dinner on it’s own, but here are some ideas if you want a side dish:

Low-Carb Deconstructed Pizza Casserole in baking dish on cutting board

Want more ideas for low-carb and Keto pizza?

When you’re craving pizza but don’t want the carbs, there are more ideas from Kalyn’s Kitchen or around the web in my huge collection of Low-Carb Pizza Recipes. And most of those recipes are also Keto and gluten-free.

Weekend Food Prep:

This Keto Pizza Casserole recipe has been added to a category called Weekend Food Prep where you’ll find recipes you can prep or cook on the weekend and eat during the week!

Low-Carb Deconstructed Pizza Casserole in baking dish on cutting board
Yield: 6 servings

Low-Carb Deconstructed Pizza Casserole

Prep Time 25 minutes
Cook Time 25 minutes
Total Time 50 minutes

Low-Carb Deconstructed Pizza Casserole is a comfort food casserole the whole family will enjoy! And this tasty pizza casserole is also suitable for Keto and gluten-free, so enjoy!

Ingredients

  • 1 can diced tomatoes, well drained ((14.5 oz. can; do not use petite dice tomatoes)
  • 5 links uncooked turkey or pork Italian sausage (19.5 oz.)
  • 2 tsp. + 2 tsp. olive oil
  • 1/2 tsp. dried oregano
  • salt and fresh-ground pepper to taste (I didn't use much salt.)
  • 12 oz. fresh mushrooms, washed and cut into thick slices (I used brown Cremini mushrooms.)
  • 1 1/2 cups grated Mozzarella cheese
  • 15 slices pepperoni, cut in half (I used regular pepperoni, but you can use turkey pepperoni if you prefer)

Instructions

  1. Preheat oven to 400F/200C.
  2. Spray an 8 inch x 11 inch glass casserole dish with non-stick spray or olive oil.
  3. Pour the diced tomatoes into a colander placed in the sink and rinse with cold water. Let tomatoes drain a minute or two, then spread them out on paper towels to dry (or blot dry with another paper towel on top.)
  4. While tomatoes dry, heat 2 tsp. olive oil in a large non-stick frying pan, squeeze the sausage out of the casing, and cook sausage over medium-high heat until it's nicely browned, breaking it apart as it cooks. (I use an old-fashioned potato masher (affiliate link) to break the sausage apart.)
  5. While sausage cooks, wash mushrooms, pat dry, and slice into thick slices.
  6. When the sausage is done make a layer of sausage in the bottom of the casserole dish and top with the drained tomatoes, spreading them out over the top of the sausage.
  7. Season with dried oregano, salt, and fresh-ground black pepper. (I didn't use much salt.)
  8. Rinse out the pan if needed, then heat the other 2 tsp. of olive oil over medium-high heat. When the pan is hot add the mushrooms and cook, stirring a few times, until all the liquid is released and the mushrooms are starting to brown.
  9. Layer the mushrooms over the sausage-tomato mixture.
  10. Cut pepperoni in half.
  11. Sprinkle the grated Mozzarella over the top of the casserole and lay the pepperoni pieces on top of the cheese, spacing them evenly so the whole top is covered with pepperoni.
  12. Bake about 25 minutes, or until the cheese is melted and starting to brown.
  13. Serve this low-carb and Keto pizza casserole hot, and enjoy!

Notes

I used my favorite turkey Italian sausageย for this recipe; use pork sausage if you prefer.

This recipe created by Kalyn.

Nutrition Information

Yield

6

Serving Size

1

Amount Per Serving Calories 289Total Fat 18gSaturated Fat 7gUnsaturated Fat 10gCholesterol 85mgSodium 561mgCarbohydrates 6gFiber 2gSugar 3gProtein 26g

Nutrition information is automatically calculated by the Recipe Plug-In I am using. I am not a nutritionist and cannot guarantee 100% accuracy, since many variables affect those calculations.

Did you make this recipe?

Did you make this recipe? Please leave a star rating (under the PRINT button in the recipe) or share a photo of your results on Instagram! THANKS!

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Low-Carb Diet / Low-Glycemic Diet / South Beach Diet Suggestions:
This pizza casserole is perfect for low-carb and Keto diets, and it’s also gluten-free. It can also work for the original South Beach Diet with the right ingredients. Low-carb diet plans will probably prefer pork sausage and pepperoni and full-fat cheese. If you’re following the original South Beach Diet, they’d recommend turkey Italian sausage, turkey pepperoni, and reduced fat Mozzarella. 

Find More Recipes Like This One:
Use Casserole Recipes to find more recipes like this one. Use the Diet Type Index to find recipes suitable for a specific eating plan. You might also like to follow Kalynโ€™s Kitchen on Pinterest, on Facebook, on Instagram, on TikTok, or on YouTube to see all the good recipes Iโ€™m sharing there.

Historical Notes for this Recipe:
This low-carb and Keto pizza casserole was first posted in 2016, and it quickly became one of the most popular casseroles on my site. The recipe was last updated with more information in 2025.

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